-----BEGIN PRIVACY-ENHANCED MESSAGE----- Proc-Type: 2001,MIC-CLEAR Originator-Name: webmaster@www.sec.gov Originator-Key-Asymmetric: MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB MIC-Info: RSA-MD5,RSA, Lm36T/2scGEQbVccpND/ed0soatZzvevuRxgzLk0avAEI2ISlyR2ledNL4HsGhBu QHCXscRuaKHfyzFjUgDJHg== 0001341004-07-003096.txt : 20071205 0001341004-07-003096.hdr.sgml : 20071205 20071205143540 ACCESSION NUMBER: 0001341004-07-003096 CONFORMED SUBMISSION TYPE: SC 13D/A PUBLIC DOCUMENT COUNT: 1 FILED AS OF DATE: 20071205 DATE AS OF CHANGE: 20071205 GROUP MEMBERS: APTAFIN S.P.A. GROUP MEMBERS: CHAUMIERE - CONSULTADORIA & SERVICOS SDC UNIPESSOAL LDA GROUP MEMBERS: DEFIANTE FARMACEUTICA L.D.A. GROUP MEMBERS: INVERLOCHY CONSULTADORIA & SERVICOS L.D.A. GROUP MEMBERS: PAOLO CAVAZZA GROUP MEMBERS: SIGMA TAU FINANZIARIA SPA GROUP MEMBERS: SIGMA-TAU INTERNATIONAL S.A. SUBJECT COMPANY: COMPANY DATA: COMPANY CONFORMED NAME: QUESTCOR PHARMACEUTICALS INC CENTRAL INDEX KEY: 0000891288 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] IRS NUMBER: 330476164 STATE OF INCORPORATION: CA FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: SC 13D/A SEC ACT: 1934 Act SEC FILE NUMBER: 005-43062 FILM NUMBER: 071286384 BUSINESS ADDRESS: STREET 1: 3260 WHIPPLE ROAD CITY: UNION CITY STATE: CA ZIP: 94587-1217 BUSINESS PHONE: 5104000700 MAIL ADDRESS: STREET 1: 3260 WHIPPLE ROAD CITY: UNION CITY STATE: CA ZIP: 94587-1217 FORMER COMPANY: FORMER CONFORMED NAME: CYPROS PHARMACEUTICAL CORP DATE OF NAME CHANGE: 19930328 FILED BY: COMPANY DATA: COMPANY CONFORMED NAME: CAVAZZA CLAUDIO CENTRAL INDEX KEY: 0001164803 FILING VALUES: FORM TYPE: SC 13D/A MAIL ADDRESS: STREET 1: VIA SUDAFRICA 20 CITY: ROME ITALY STATE: L6 ZIP: 00000 SC 13D/A 1 sc13damend.htm SCHEDULE 13D AMENDMENT sc13damend.htm

SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, DC 20549

SCHEDULE 13D
[Rule 13d-101]

INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT
TO §240.13d-1(a) AND AMENDMENTS THERETO FILED PURSUANT TO
§240.13d-2(a)
(Amendment No. 11 and Amendment No. 13)*


QUESTCOR PHARMACEUTICALS INC.
(Name of Issuer)
 
Common Stock
(Title of Class of Securities)
 
232808105
(CUSIP Number)
 
Joseph J. Giunta, Esq.
Skadden, Arps, Slate, Meagher & Flom LLP
300 South Grand Avenue
Los Angeles, CA 90071
(213) 687-5000
(Name, Address and Telephone Number of Person Authorized to Receive Notices and Communications)
 
December 20, 2006
(Date of Event Which Requires Filing of this Statement)
 

 
If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§240.13d-1(e), 240.13d-1(f) or 240.13d-(1)(g), check the following box £.
 
*The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page.
 
The information required on the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).
 


 
 
 CUSIP No.232808105
 13D
 Page 2 of 22 Pages


       
       
1
NAMES OF REPORTING PERSONS
   
         
 
Claudio Cavazza
     
         
     
2
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
(a) £
       
(b) £
         
         
3
SEC USE ONLY
     
         
       
4
SOURCE OF FUNDS
   
         
         
5
CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
 
 
PURSUANT TO ITEM 2(d) OR 2(e)
 
£
         
     
6
CITIZENSHIP OR PLACE OF ORGANIZATION
 
 
Italy
         
   
7
SOLE VOTING POWER
 
 
NUMBER OF
 
1,756,781
 
 
SHARES
     
 
BENEFICIALLY
8
SHARED VOTING POWER
 
 
OWNED BY
 
4,701,445
 
 
EACH
     
 
REPORTING
9
SOLE DISPOSITIVE POWER
 
 
PERSON WITH
 
1,756,781
 
         
   
10
SHARED DISPOSITIVE POWER
 
     
4,701,445
 
   
11
AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
   
 
6,458,226
         
   
12
CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
 
CERTAIN SHARES
   
£
         
     
13
PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
 
         
 
 9.32%
         
       
14
TYPE OF REPORTING PERSON
   
 
IN

 

 
 CUSIP No.232808105
 13D
 Page 3 of 22 Pages
 
       
       
1
NAMES OF REPORTING PERSONS
   
         
 
Paolo Cavazza
     
         
     
2
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
(a) £
       
(b) £
         
         
3
SEC USE ONLY
     
         
         
4
SOURCE OF FUNDS
   
         
     
5
CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
 
 
PURSUANT TO ITEM 2(d) OR 2(e)
 
£
         
     
6
CITIZENSHIP OR PLACE OF ORGANIZATION
 
         
 
Italy
         
   
7
SOLE VOTING POWER
 
 
NUMBER OF
 
0
 
 
SHARES
     
 
BENEFICIALLY
8
SHARED VOTING POWER
 
 
OWNED BY
 
7,797,327
 
 
EACH
     
 
REPORTING
9
SOLE DISPOSITIVE POWER
 
 
PERSON WITH
 
0
 
         
   
10
SHARED DISPOSITIVE POWER
 
     
7,797,327
 
   
11
AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
         
 
  7,797,327 
         
   
12
CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
 
CERTAIN SHARES
   
£
         
     
13
PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
 
         
 
  11.25% 
         
       
14
TYPE OF REPORTING PERSON
   
 
  IN 


 
 CUSIP No.232808105
 13D
 Page 4 of 22 Pages
 
       
       
1
NAMES OF REPORTING PERSONS
   
         
 
Sigma-Tau Finanziaria SpA
   
         
     
2
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
(a) £
       
(b) £
         
         
3
SEC USE ONLY
     
         
       
4
SOURCE OF FUNDS
   
         
     
5
CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
 
 
PURSUANT TO ITEM 2(d) OR 2(e)
 
£
         
     
6
CITIZENSHIP OR PLACE OF ORGANIZATION
 
         
 
Italy
         
   
7
SOLE VOTING POWER
 
 
NUMBER OF
 
0
 
 
SHARES
     
 
BENEFICIALLY
8
SHARED VOTING POWER
 
 
OWNED BY
 
0
 
 
EACH
     
 
REPORTING
9
SOLE DISPOSITIVE POWER
 
 
PERSON WITH
 
0
 
         
   
10
SHARED DISPOSITIVE POWER
 
     
0
 
   
11
AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
         
 
0
         
   
12
CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
 
CERTAIN SHARES
   
£
         
     
13
PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
 
         
 
 0%
         
       
14
TYPE OF REPORTING PERSON
   
 
CO

 

 
 CUSIP No.232808105
 13D
 Page 5 of 22 Pages

 
       
       
1
NAMES OF REPORTING PERSONS
   
         
 
Sigma-Tau International S.A.
   
         
     
2
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
(a) £
       
(b) £
         
         
3
SEC USE ONLY
     
         
       
4
SOURCE OF FUNDS
   
         
     
5
CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
 
 
PURSUANT TO ITEM 2(d) OR 2(e)
 
£
         
     
6
CITIZENSHIP OR PLACE OF ORGANIZATION
 
         
 
Luxembourg
         
   
7
SOLE VOTING POWER
 
 
NUMBER OF
 
0
 
 
SHARES
     
 
BENEFICIALLY
8
SHARED VOTING POWER
 
 
OWNED BY
 
0
 
 
EACH
     
 
REPORTING
9
SOLE DISPOSITIVE POWER
 
 
PERSON WITH
 
0
 
         
   
10
SHARED DISPOSITIVE POWER
 
     
0
 
   
11
AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
         
 
0
         
   
12
CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
 
CERTAIN SHARES
   
£
         
     
13
PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
 
         
 
0%
         
       
14
TYPE OF REPORTING PERSON
   
 
CO

 

 
 CUSIP No.232808105
 13D
 Page 6 of 22 Pages
 

       
       
1
NAMES OF REPORTING PERSONS
   
         
 
Defiante Farmaceutica L.D.A.
   
         
     
2
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
(a) £
       
(b) £
         
         
3
SEC USE ONLY
     
         
       
4
SOURCE OF FUNDS
   
         
     
5
CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
 
 
PURSUANT TO ITEM 2(d) OR 2(e)
 
£
         
     
6
CITIZENSHIP OR PLACE OF ORGANIZATION
 
         
 
Portugal
         
   
7
SOLE VOTING POWER
 
 
NUMBER OF
 
0
 
 
SHARES
     
 
BENEFICIALLY
8
SHARED VOTING POWER
 
 
OWNED BY
 
0
 
 
EACH
     
 
REPORTING
9
SOLE DISPOSITIVE POWER
 
 
PERSON WITH
 
0
 
         
   
10
SHARED DISPOSITIVE POWER
 
     
0
 
   
11
AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
         
 
0
         
   
12
CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
 
CERTAIN SHARES
   
£
         
     
13
PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
 
         
 
 0%
         
       
14
TYPE OF REPORTING PERSON
   
 
CO
 


 
 CUSIP No.232808105
 13D
 Page 7 of 22 Pages

 
       
       
1
NAMES OF REPORTING PERSONS
   
         
 
Aptafin S.p.A.
   
         
     
2
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
(a) £
       
(b) £
         
         
3
SEC USE ONLY
     
         
       
4
SOURCE OF FUNDS
   
         
     
5
CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
 
 
PURSUANT TO ITEM 2(d) OR 2(e)
 
£
         
         
     
6
CITIZENSHIP OR PLACE OF ORGANIZATION
 
         
 
Italy
         
   
7
SOLE VOTING POWER
 
 
NUMBER OF
 
0
 
 
SHARES
     
 
BENEFICIALLY
8
SHARED VOTING POWER
 
 
OWNED BY
 
7,797,327
 
 
EACH
     
 
REPORTING
9
SOLE DISPOSITIVE POWER
 
 
PERSON WITH
 
0
 
         
   
10
SHARED DISPOSITIVE POWER
 
     
7,797,327
 
   
11
AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
         
 
7,797,327
         
   
12
CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
 
CERTAIN SHARES
   
£
         
     
13
PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
 
         
 
11.25%
         
       
14
TYPE OF REPORTING PERSON
   
 
CO



 
 CUSIP No.232808105
 13D
 Page 8 of 22 Pages
 

       
       
1
NAMES OF REPORTING PERSONS
   
         
 
Chaumiere – Consultadoria & Servicos SDC Unipessoal LDA
         
     
2
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
(a) £
       
(b) £
         
         
3
SEC USE ONLY
     
         
       
4
SOURCE OF FUNDS
   
         
 
 
     
     
5
CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
 
 
PURSUANT TO ITEM 2(d) OR 2(e)
 
£
         
         
     
6
CITIZENSHIP OR PLACE OF ORGANIZATION
 
         
 
Portugal
         
   
7
SOLE VOTING POWER
 
 
NUMBER OF
 
0
 
 
SHARES
     
 
BENEFICIALLY
8
SHARED VOTING POWER
 
 
OWNED BY
 
7,248,227
 
 
EACH
     
 
REPORTING
9
SOLE DISPOSITIVE POWER
 
 
PERSON WITH
 
0
 
         
   
10
SHARED DISPOSITIVE POWER
 
     
7,248,227
 
   
11
AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
         
 
7,248,227
         
   
12
CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
 
CERTAIN SHARES
   
£
         
     
13
PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
 
         
 
10.46%
         
       
14
TYPE OF REPORTING PERSON
   
 
CO



 
 CUSIP No.232808105
 13D
 Page 9 of 22 Pages
 

       
       
1
NAMES OF REPORTING PERSONS
   
         
 
Inverlochy Consultadoria & Servicos L.D.A.
 
         
     
2
CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
(a) £
       
(b) £
         
         
3
SEC USE ONLY
     
         
       
4
SOURCE OF FUNDS
   
         
     
5
CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED
 
 
PURSUANT TO ITEM 2(d) OR 2(e)
 
£
         
         
     
6
CITIZENSHIP OR PLACE OF ORGANIZATION
 
         
 
Portugal
         
   
7
SOLE VOTING POWER
 
 
NUMBER OF
 
0
 
 
SHARES
     
 
BENEFICIALLY
8
SHARED VOTING POWER
 
 
OWNED BY
 
4,701,445
 
 
EACH
     
 
REPORTING
9
SOLE DISPOSITIVE POWER
 
 
PERSON WITH
 
0
 
         
   
10
SHARED DISPOSITIVE POWER
 
     
4,701,445
 
   
11
AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
         
 
4,701,445
         
   
12
CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES
 
CERTAIN SHARES
   
£
         
     
13
PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
 
         
 
6.78%
         
       
14
TYPE OF REPORTING PERSON
   
 
CO

 

 
 CUSIP No.232808105
 13D
 Page 10 of 22 Pages

 
Amendment No. 11 and
Amendment No. 13 to
Statement on Schedule 13D

           This Amendment No. 11 (the “Amendment No. 11”) amends the Statement on Schedule 13D filed with the Securities and Exchange Commission (“SEC”) on March 25, 2002 (the “Sigma/Defiante Schedule 13D”), as amended, relating to shares of the common stock, no par value (the “Common Stock”), of Questcor Pharmaceuticals, Inc., a California corporation (“Questcor”).  This Amendment No. 13 (the “Amendment No. 13” and, together with the Amendment No. 11, this “Statement”) amends the Statement on Schedule 13D, filed with the SEC on August 7, 2001 (the “Cavazza/Sigma Schedule 13D” and, together with the Sigma/Defiante Schedule 13D, the “Schedule 13Ds”), as amended, relating to the shares of Common Stock.  Pursuant to Rule 13d-2 of Regulation 13D-G promulgated under the Securities Exchange Act of 1934, as amended (the “Act”), this Amendment No. 11 is being filed on behalf of Sigma Tau Finanziaria SpA, an Italian corporation (“Sigma Tau”) and Defiante Farmaceutica L.D.A., a Portuguese corporation (“Defiante”) (formerly known as Defiante Farmaceutica Unipessoal L.D.A.), and this Amendment No. 13 is being filed on behalf of Sigma-Tau International S.A., a Luxembourg corporation (“Sigma Tau International”) (formerly known as Sigma-Tau Finance Holding S.A.), Aptafin S.p.A., an Italian corporation (“Aptafin”), Chaumiere - Consultadoria & Servicos SDC Unipessoal LDA, a Portuguese corporation (“Chaumiere”), Inverlochy Consultadoria & Servicos L.D.A., a Portuguese corporation (“Inverlochy”), Mr. Claudio Cavazza (“Mr. C. Cavazza”) and Mr. Paolo Cavazza (“Mr. P. Cavazza” and, together with Mr. C. Cavazza, Sigma Tau International, Aptafin, Chaumiere, Inverlochy, Defiante and Sigma Tau, the “Reporting Persons”).

Previously, the Reporting Persons affirmed membership in a “group” for purposes of Section 13(d) and 13(g) of the Act.  Effective as of the date of the transactions reported in Amendment No. 9 to the Sigma/Defiante Schedule 13D and Amendment No. 11 to the Cavazza/Sigma Schedule 13D, the Reporting Persons were no longer members of a “group.”  In addition, effective with the transactions reported in Amendment No. 9 to the Sigma/Defiante Schedule 13D and Amendment No. 11 to the Cavazza/Sigma Schedule 13D, Sigma Tau International, Sigma Tau and Defiante ceased to beneficially own any shares of Common Stock.  As such, following the filing of this Statement, Sigma Tau International, Sigma Tau and Defiante will cease to file reports on Schedule 13D with respect to the Common Stock.

Item 2.                      Identity and Background.
 
Item 2 of the Schedule 13Ds are hereby amended by the addition of the following:
 
As a result of the transactions reported in Amendment No. 9 to the Sigma/Defiante Schedule 13D and Amendment No. 11 to the Cavazza/Sigma Schedule 13D, Sigma Tau International, Sigma Tau and Defiante will cease to be Reporting Persons following the filing of this Statement.
 
Item 5.                      Interest in Securities of the Issuer.
 
Item 5 of the Schedule 13Ds are hereby amended as follows:
 
(a)           Percentage interest calculations for the Reporting Persons are based upon Questcor having 69,296,099 shares of Common Stock outstanding as of November 1, 2007 (the “Outstanding Shares”), as reported by Questcor in Questcor’s Form 10-Q filed with the SEC on November 14, 2007.

Mr. C. Cavazza
 
Pursuant to Rule 13d-3 of the Act, Mr. C. Cavazza may be deemed to be the beneficial owner of 6,458,226 shares of Common Stock, which constitutes approximately 9.32% of the Outstanding Shares.
 
Mr. P. Cavazza
 
Pursuant to Rule 13d-3 of the Act, Mr. P. Cavazza may be deemed to be the beneficial owner of 7,797,327 shares of Common Stock, which constitutes approximately 11.25% of the Outstanding Shares.
 
 

 
 CUSIP No.232808105
 13D
 Page 11 of 22 Pages
 
 
Sigma Tau International
 
Effective with the transactions reported in Amendment No. 9 to the Sigma/Defiante Schedule 13D and Amendment No. 11 to the Cavazza/Sigma Schedule 13D, Sigma Tau International ceased to beneficially own any shares of Common Stock pursuant to Rule 13d-3 of the Act.
 
Sigma Tau
 
Effective with the transactions reported in Amendment No. 9 to the Sigma/Defiante Schedule 13D and Amendment No. 11 to the Cavazza/Sigma Schedule 13D, Sigma Tau ceased to beneficially own any shares of Common Stock pursuant to Rule 13d-3 of the Act.
 
Defiante
 
Effective with the transactions reported in Amendment No. 9 to the Sigma/Defiante Schedule 13D and Amendment No. 11 to the Cavazza/Sigma Schedule 13D, Defiante ceased to beneficially own any shares of Common Stock pursuant to Rule 13d-3 of the Act.
 
Aptafin
 
Pursuant to Rule 13d-3 of the Act, Aptafin may be deemed to be the beneficial owner of 7,797,327 shares of Common Stock, which constitutes approximately 11.25% of the Outstanding Shares.
 
Chaumiere
 
Pursuant to Rule 13d-3 of the Act, Chaumiere may be deemed to be the beneficial owner of 7,248,227 shares of Common Stock, which constitutes approximately 10.46% of the Outstanding Shares.
 
Inverlochy
 
Pursuant to Rule 13d-3 of the Act, Inverlochy may be deemed to be the beneficial owner of 4,701,445 shares of Common Stock, which constitutes approximately 6.78% of the Outstanding Shares.
 
Except as set forth above, none of the Reporting Persons nor any of the persons listed on Schedule A beneficially owns any other shares of Common Stock.
 
(b)           Mr. C. Cavazza
 
The number of shares of Common Stock as to which Mr. C. Cavazza has the sole power to vote or direct the vote is 1,756,781.  The number of shares of Common Stock as to which Mr. C. Cavazza shares the power to vote or direct the vote is 4,701,445.  The number of shares of Common Stock as to which Mr. C. Cavazza has the sole power to dispose or direct the disposition is 1,756,781.  The number of shares of Common Stock as to which Mr. C. Cavazza shares the power to dispose or direct the disposition is 4,701,445.
 
Mr. P. Cavazza
 
The number of shares of Common Stock as to which Mr. P. Cavazza has the sole power to vote or direct the vote is zero.  The number of shares of Common Stock as to which Mr. P. Cavazza shares the power to vote or direct the vote is 7,797,327.  The number of shares of Common Stock as to which Mr. P. Cavazza has the sole power to dispose or direct the disposition is zero.  The number of shares of Common Stock as to which Mr. P. Cavazza shares the power to dispose or direct the disposition is 7,797,327.
 
 

 
 CUSIP No.232808105
 13D
 Page 12 of 22 Pages
 
 
Sigma Tau International
 
The number of shares of Common Stock as to which Sigma Tau International has the sole power to vote or direct the vote is zero.  The number of shares of Common Stock as to which Sigma Tau International shares the power to vote or direct the vote is zero.  The number of shares of Common Stock as to which Sigma Tau International has the sole power to dispose or direct the disposition is zero.  The number of shares of Common Stock as to which Sigma Tau International shares the power to dispose or direct the disposition is zero.
 
Sigma Tau
 
The number of shares of Common Stock as to which Sigma Tau has the sole power to vote or direct the vote is zero.  The number of shares of Common Stock as to which Sigma Tau shares the power to vote or direct the vote is zero.  The number of shares of Common Stock as to which Sigma Tau has the sole power to dispose or direct the disposition is zero.  The number of shares of Common Stock as to which Sigma Tau shares the power to dispose or direct the disposition is zero.
 
Defiante
 
The number of shares of Common Stock as to which Defiante has the sole power to vote or direct the vote is zero.  The number of shares of Common Stock as to which Defiante shares the power to vote or direct the vote is zero.  The number of shares of Common Stock as to which Defiante has the sole power to dispose or direct the disposition is zero.  The number of shares of Common Stock as to which Defiante shares the power to dispose or direct the disposition is zero.

Aptafin
 
The number of shares of Common Stock as to which Aptafin has the sole power to vote or direct the vote is zero.  The number of shares of Common Stock as to which Aptafin shares the power to vote or direct the vote is 7,797,327.  The number of shares of Common Stock as to which Aptafin has the sole power to dispose or direct the disposition is zero.  The number of shares of Common Stock as to which Aptafin shares the power to dispose or direct the disposition is 7,797,327.

Chaumiere
 
The number of shares of Common Stock as to which Chaumiere has the sole power to vote or direct the vote is zero.  The number of shares of Common Stock as to which Chaumiere shares the power to vote or direct the vote is 7,248,227.  The number of shares of Common Stock as to which Chaumiere has the sole power to dispose or direct the disposition is zero.  The number of shares of Common Stock as to which Chaumiere shares the power to dispose or direct the disposition is 7,248,227.

Inverlochy
 
The number of shares of Common Stock as to which Inverlochy has the sole power to vote or direct the vote is zero.  The number of shares of Common Stock as to which Inverlochy shares the power to vote or direct the vote is 4,701,445.  The number of shares of Common Stock as to which Inverlochy has the sole power to dispose or direct the disposition is zero.  The number of shares of Common Stock as to which Inverlochy shares the power to dispose or direct the disposition is 4,701,445.

(e)           On December 20, 2006, Sigma Tau International, Sigma Tau and Defiante ceased to be the beneficial owner of more than five percent of the Common Stock.

Item 7.
Material to be Filed as Exhibits.
 
Item 7 of the Schedule 13Ds are hereby amended to add the following:
 
EXHIBIT 15– Joint Filing Agreement dated December 21, 2006 by and between the Reporting Persons (incorporated by reference to Exhibit 7 to the Schedule 13Ds).
 
 

 
 CUSIP No.232808105
 13D
 Page 13 of 22 Pages
 
 
 
EXHIBIT 16 – Power of Attorney dated December 21, 2006 by Inverlochy (incorporated by reference to Exhibit 8 to the Schedule 13Ds).
 
EXHIBIT 17 – Power of Attorney dated April 15, 2005 by Chaumiere – Consultadoria & Servicos SDC Unipessoal LDA (incorporated by reference to Exhibit 2 to the Schedule 13Ds).
 
EXHIBIT 18 – Power of Attorney dated April 8, 2003 by and between Claudio Cavazza, Paolo Cavazza, Sigma-Tau International S.A., Sigma-Tau Finanziaria SpA, Defiante Farmaceutica L.D.A. and Aptafin S.p.A. (incorporated by reference to Exhibit 1 of Form 4, filed with the SEC on May 9, 2003, relating to the shares of Common Stock)
 

 


 
 CUSIP No.232808105
 13D
 Page 14 of 22 Pages
 
 
 
Signatures

 
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement with respect to Claudio Cavazza is true, complete and correct.
 
Dated:  December 4, 2007
 
 
CLAUDIO CAVAZZA
 
       
       
 
By:
/s/ Antonio Nicolai
 
   
Antonio Nicolai, Attorney-in-fact for
 
   
Claudio Cavazza
 
       

 
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement with respect to Paolo Cavazza is true, complete and correct.
 
Dated:  December 4, 2007
 
 
PAOLO CAVAZZA
 
       
       
 
By:
/s/ Antonio Nicolai
 
   
Antonio Nicolai, Attorney-in-fact for
 
   
Paolo Cavazza
 
       

 
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement with respect to Sigma-Tau Finanziaria SpA is true, complete and correct.
 
Dated:  December 4, 2007
 
 
SIGMA-TAU FINANZIARIA SPA
 
       
       
 
By:
/s/ Antonio Nicolai
 
   
Antonio Nicolai, Attorney-in-fact for
 
   
Sigma-Tau Finanziari SpA
 
       

 
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement with respect to Sigma-Tau International S.A. is true, complete and correct.
 
Dated:  December 4, 2007
 
 
SIGMA-TAU INTERNATIONAL S.A.
 
       
       
 
By:
/s/ Antonio Nicolai
 
   
Antonio Nicolai, Attorney-in-fact for
 
   
Sigma-Tau International S.A.
 
 
 
 

 
 
 CUSIP No.232808105
 13D
 Page 15 of 22 Pages
 
 
 
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement with respect to Defiante Farmaceutica L.D.A. is true, complete and correct.
 
Dated:  December 4, 2007
 
 
DEFIANTE FARMACEUTICA L.D.A.
 
       
       
 
By:
/s/ Antonio Nicolai
 
   
Antonio Nicolai, Attorney-in-fact for
 
   
Defiante Farmaceutica L.D.A.
 
       

 
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement with respect to Aptafin S.p.A. is true, complete and correct.
 
Dated:  December 4, 2007
 
 
APTAFIN S.P.A.
 
       
       
 
By:
/s/ Antonio Nicolai
 
   
Antonio Nicolai, Attorney-in-fact for
 
   
Aptafin S.p.A.
 
       

 
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement with respect to Chaumiere - Consultadoria & Servicos SDC Unipessoal LDA is true, complete and correct.
 
Dated:  December 4, 2007
 
 
CHAUMIERE - CONSULTADORIA & SERVICOS SDC UNIPESSOAL LDA
 
       
       
 
By:
/s/ Antonio Nicolai
 
   
Antonio Nicolai, Attorney-in-fact for Chaumiere - Consultadoria & Servicos SDC Unipessoal LDA
 
       

 



 CUSIP No.232808105
 13D
 Page 16 of 22 Pages
 
 
 
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement with respect to Inverlochy Consultadoria & Servicos L.D.A. is true, complete and correct.
 
Dated:  December 4, 2007
 
 
INVERLOCHY CONSULTADORIA & SERVICOS L.D.A.
 
       
       
 
By:
/s/ Antonio Nicolai
 
   
Antonio Nicolai, Attorney-in-fact for Inverlochy Consultadoria & Servicos L.D.A.
 
       

 
The original statement shall be signed by each person on whose behalf the statement is filed or his authorized representative.  If the statement is signed on behalf of a person by his authorized representative (other than an executive officer or general partner of the filing person), evidence of the representative’s authority to sign on behalf of such person shall be filed with the statement, provided, however, that a power of attorney for this purpose which is already on file with the Commission may be incorporated by reference.  The name of any title of each person who signs the statement shall be typed or printed beneath his signature.
 
 
Attention:  Intentional misstatements or omissions of fact constitute Federal criminal violations (see 18 U.S.C. 1001).


 
 CUSIP No.232808105
 13D
 Page 17 of 22 Pages

 
Schedule A
 
EXECUTIVE OFFICERS AND DIRECTORS
 
Sigma Tau Finanziaria SpA
 
NAME
ADDRESS
TITLE
CITIZENSHIP
 
Claudio Cavazza
 
via Pontina Km. 30,400,
00040 Pomezia (Rome) Italy
 
President
 
Italian
 
Ugo Di Francesco
 
via Sudafrica,20,
00144 Rome Italy-
 
Vice President and Chief
Executive Officer
 
Italian
 
Antonio Nicolai
 
via Sudafrica,20,
00144 Rome Italy
 
Managing Director
 
Italian
 
Mauro Bove
 
via Sudafrica,20,
00144 Rome Italy
 
Managing Director
 
Italian
 
Stefano Marino
 
via Pontina Km. 30,400
00040 Pomezia (Rome) Italy
 
Managing Director
 
Italian
 
Trevor M. Jones CBA
 
Woodhyrst House
18 Friths Drive
REIGATE Surrey
Great Britain
 
Director
 
British
 
Emilio Platè
 
via Pontina Km. 30,400
00040 Pomezia (Rome) Italy
 
Director
 
Italian
 
Mario Artali
 
via Sudafrica,20,
00144 Rome Italy
 
Director
 
Italian
 
Enrico Cavazza
 
via Pontina Km. 30,400
00040 Pomezia (Rome) Italy
 
Director
 
Italian
 
Marco Cerrina Feroni
 
Piazza Paolo Ferrari 10
20121 Milano, Italy
 
Director
 
Italian

 

 


 
 CUSIP No.232808105
 13D
 Page 18 of 22 Pages

 
Schedule A
 
EXECUTIVE OFFICERS AND DIRECTORS
 
Sigma-Tau International S.A.
 
NAME
ADDRESS
TITLE
CITIZENSHIP
 
Ugo Di Francesco
 
via Sudafrica,20,
00144 Rome Italy-
 
President
 
Italian
 
Jonathan Lepage
 
Bd. Du Prince Henri 19-21
L-1724 Luxembourg
 
Director
 
Belgian
 
Luca Checchinato
 
Bd. Du Prince Henri 19-21
L-1724 Luxembourg
 
Director
 
Italian
 
Antonio Nicolai
 
via Sudafrica,20,
00144 Rome Italy
 
Director
 
Italian
       
Mauro Bove
via Sudafrica,20,
00144Rome Italy
Director
Italian
 
Gustave Stoffel
 
18 Avenue De La Porte Neuve
L-2227 Luxembourg
 
Director
 
Luxembourg
 
Dominique Audia
 
Bd. Du Prince Henri 19-21
L-1724 Luxembourg
 
Director
 
French


 
 CUSIP No.232808105
 13D
 Page 19 of 22 Pages

 
Schedule A
 
EXECUTIVE OFFICERS AND DIRECTORS
 
Defiante Farmaceutica L.D.A.
 
NAME
ADDRESS
TITLE
CITIZENSHIP
 
Antonio Nicolai
 
via Sudafrica,20,
00144 Rome Italy
 
Director
 
Italian
 
Raffaele Sanguigni
 
Via Pontina Km. 30.400 – 00040 Pomezia
(Rome) Italy
 
Director
 
Italian
 
Paulo Alexandre da Mota Viegas
 
Rua dos Tanoeiros, 12º - 2º e 3º - Funchal - Madeira -
Portugal 9000
 
Director
 
Portuguese
 
Pedro Moreira da Cruz Quintas
 
Rua dos Ferreiros, 260 - Funchal - Madeira -
ortugal 9000-082
 
Director
 
Portuguese
 
Carla Emanuel Arruda Jardim Fernandes
 
Rua dos Ferreiros, 260 - Funchal - Madeira -
Portugal 9000-082
 
Director
 
Portuguese
 



 
 CUSIP No.232808105
 13D
 Page 20 of 22 Pages

 
Schedule A
 
EXECUTIVE OFFICERS AND DIRECTORS
 
Aptafin S.p.A.
 
NAME
ADDRESS
TITLE
CITIZENSHIP
 
Cristina Cavazza
 
Viale Shakespeare, 47
00144 Rome Italy
 
President
 
Italian
 
Maurizio Terenzi
 
via Sudafrica,20,
00144 Rome Italy-
 
Managing Director
 
Italian
 
Antonio Nicolai
 
via Sudafrica,20,
00144 Rome Italy-
 
Director
 
Italian
 
Emanuela Cavazza
 
Viale Shakespeare 47
00144 Rome Italy-
 
Director
 
Italian
 



 
 CUSIP No.232808105
 13D
 Page 21 of 22 Pages
 

 
Schedule A
 
EXECUTIVE OFFICERS AND DIRECTORS
 
Inverlochy Consultadoria & Servicos L.D.A.
 
NAME
ADDRESS
TITLE
CITIZENSHIP
 
Roberto Carlos de
Castro Abreu
 
Avenida da República, 32, 4.º
Esquerdo, 1050-193 Lisboa,
Portugal
 
Director
 
Portuguese
 
João Josè de Freitas
Rodrigues
 
Avenida da República, 32, 4.º
Esquerdo, 1050-193 Lisboa,
Portugal
 
Director
 
Portuguese





 
 
 CUSIP No.232808105
 13D
 Page 22 of 22 Pages
 

Schedule A
 
EXECUTIVE OFFICERS AND DIRECTORS
 
Chaumiere - Consultadoria & Servicos SDC Unipessoal LDA
 
NAME
ADDRESS
TITLE
CITIZENSHIP
    
Roberto Carlos de
Castro Abreu
Avenida da República, 32, 4.º Esquerdo,
1050-193 Lisboa,
Portugal
Director
Portuguese
    
João Josè de Freitas
Rodrigues
Avenida da República, 32, 4.º
Esquerdo, 1050-193 Lisboa,
Portugal
Director
Portuguese


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